Are you ready to have the weekend of a lifetime in the USA? There are so many weekend trip options, whether you’re looking for city breaks in iconic cities like San Francisco and New York City or adventurous retreats to national parks.
Weekend getaways in the USA can be city-focused, with art galleries and landmark sightseeing – who fancies a view from the Empire State Building? Alternatively, you could head rural to somewhere like Glacier National Park for hiking trails and natural beauty.
You could easily spend a lifetime traveling the USA in immense detail. But, equally, the country has some places ideally suited to short stays.
East Coast
1. Boston, Massachusetts
Boston is a great place to immerse yourself in academia and educational sightseeing. As Massachusetts’s capital, Boston has some of the state’s best attractions, including Harvard University, the Museum of Fine Arts, and the Museum of Science. However, Boston also has its own story to offer. You can tour the Boston Tea Party Ships & Museum and walk the hallowed Freedom Trail to learn more about the city’s Civil War history. When you only have a weekend, it’s helpful to have a destination with a clear theme and specialty, like Boston’s academia and Tea Party history.
Boston is incredible as a weekend getaway. It even has the nickname ‘The Walking City’ because it’s so well-suited to exploring on foot. If you want a city break on the East Coast, Boston is a fabulous choice for a short but sweet historical insight into US history.
Where to Stay: The Newbury Boston.
Insider Tip: If you can, a day trip to the Salem Witch Museum for darker history when visiting Boston.
2. Charleston, South Carolina
Charleston is another hotspot for history buffs. This historic South Carolina city was founded in 1670, and it has preserved beautiful cobblestone streets and antebellum houses that make visiting feel like stepping inside a time capsule. It’s great for those who want a more immersive history, providing a real snapshot of original architecture.
The French Quarter and Battery Districts are non-negotiable neighborhoods to visit for the typical Charleston aesthetic. If you want more Civil Rights and tragic slavery history, visit the Aiken-Rhett House Museum and the Old Exchange and Provost Dungeon. Joe Riley Waterfront Park is also beautiful for a light-hearted stroll with views over Charleston Harbor and is within easy walking distance of the city center.
Charleston is walkable and heavy on its immersive history, making it one of the best weekend getaways in the USA. Everything is well-preserved, and you’ll learn so much, even in a short weekend break, so we had to add it to this guide.
Where to Stay: Market Pavilion Hotel.
Insider Tip: Head to Charleston City Market for souvenir shopping. It has more than 300 vendors daily.
3. Savannah, Georgia
Savannah has similar antebellum architecture and a time capsule feel – even home to horse-drawn carriages around its central Historic District. You’ve got quaint shops, sleepy oak trees, and cobbled squares. You can walk Savannah’s waterfront along the Savannah River, visit the American Prohibition Museum, and take guided tours of the Italianate Mercer Williams House Museum. When it comes to weekend getaways in the USA, Savannah is a beautiful choice and very aesthetic.
However, Savannah comes into its own with haunted stories and runs regular ghost tours of the cemeteries and Historic District. It’s especially famous for Bonaventure Cemetery and Colonial Park Cemetery, attracting thrill-seeking tourists looking for after-hours spooky tours.
Savannah is compact enough to explore on a weekend. It has a beautiful atmosphere and stunning architecture. It also has a fun haunted quality, which is great for maximizing your evening entertainment—if you feel brave enough.
Where to Stay: Bellwether House.
Insider Tip: Book a haunted Savannah pub crawl if you want to mix ghost hunting with partying.
4. Washington DC
Washington, DC, is a big deal when it comes to weekend trips on the East Coast. It’s the alpha and omega of all US history and the capital of the country, home to significant landmarks like Capitol Hill and the White House. Washington, DC, is an ideal weekend getaway if you are interested in politics or political history.
There are many things to do, including visiting the National Mall, touring the White House, and sightseeing the various Smithsonian museums. From March to April, Washington DC is best known for gorgeous cherry blossoms all around the Tidal Basin, with over 3,000 cherry blossom trees in bloom.
Washington, DC, is a city center just made to walk around. Every inch of its parks has historical and geopolitical nods, whether the Japanese gift of the cherry blossoms or the Lincoln Memorial.
Where to Stay: Hotel Madera.
Insider Tip: Pack some sturdy footwear because Washington, DC, is best seen on foot.
5. Miami, Florida
Miami is a classic addition to these best weekend getaways in the USA. Sunny South Beach is an easy sell, with its art deco beach architecture and flamboyant culture. Miami is known for its beach living and great year-round weather. It’s where to head if you want culture, partying, and a relaxing beach break all rolled into one.
Visit the city’s art museums, including the Perez Art Museum and all the art galleries around South Beach. However, if you only have a weekend, Miami is the perfect time to sunbathe, play beach volleyball, or snap pictures of art deco beach buildings.
Miami is laidback and artistic, but it mostly has stunning beaches and iconic city status. It’s an excellent choice for a weekend trip.
Where to Stay: We’ve got a full guide on where to stay in Miami here.
Insider Tip: If you can, add an extra day to your trip so you can squeeze in a day trip to the Florida Keys or Everglades.
6. New York City, New York
New York City needs little introduction and is clearly one of the best weekend getaways in the USA. You can climb the Empire State Building, visit a national museum or two, walk Central Park, or take the Staten Island ferry past the Statue of Liberty. The whole city is rammed with activities from sunrise to sunrise – hence its affectionate nickname of the ‘city that never sleeps’. Throughout the day, you have thousands of observation platforms in iconic towers, museums, and unique attractions like the 9/11 Museum and Memorial. After hours, you have things like Broadway shows and cocktail bars.
The only thing we’d say about New York City is to choose your location wisely to maximize sightseeing time and to head there with a game plan. If you only visit for two days, you’ll need to be pretty savage with your itinerary. Here’s our perfect one-day itinerary if you need any inspiration.
Where to Stay: The NoMad Hotel.
Insider Tip: Buy an NYC CityPASS in advance to save money on attractions and transport. You can use it for the Statue of Liberty and Empire State Building.
West Coast
7. San Francisco, California
San Francisco is a must-visit on any West Coast itinerary. It’s iconic for the Golden Gate Bridge, but it’s also a city with a rich cultural and culinary scene. You can ride the famous cable cars, explore neighborhoods like Chinatown and the Mission District, and indulge in some of the best seafood on the West Coast. Don’t miss visiting Alcatraz Island for a glimpse into the city’s history.
San Francisco is known for its diverse neighborhoods, so whether you’re interested in art, history, or food, you’ll find something to explore. And with its mild year-round climate, it’s a great destination for a weekend getaway.
Where to Stay: Hotel Nikko San Francisco.
Insider Tip: Visit the Ferry Building Marketplace for gourmet food and local artisan products.
8. Los Angeles, California
Los Angeles offers a mix of glamorous attractions and laid-back beach vibes. You can spend your weekend exploring iconic spots like Hollywood Boulevard, Griffith Observatory, and the Getty Center. Don’t forget to take a stroll along Venice Beach and enjoy the eclectic atmosphere.
Los Angeles is a sprawling city, so it’s a good idea to plan your itinerary based on the areas you want to explore. Whether you’re into film, music, or outdoor activities, there’s something for everyone in LA.
Where to Stay: The Ritz-Carlton, Los Angeles.
Insider Tip: Take a hike to the Hollywood Sign for panoramic views of the city.
9. Seattle, Washington
Seattle is known for its vibrant arts scene, stunning natural beauty, and, of course, its coffee culture. You can spend your weekend exploring attractions like the Space Needle, Pike Place Market, and the Museum of Pop Culture. Don’t miss taking a ferry ride to Bainbridge Island for beautiful views of the city skyline.
Seattle’s diverse neighborhoods offer something for everyone, whether you’re interested in shopping, dining, or outdoor adventures. And with its picturesque setting between Puget Sound and the Cascade Mountains, it’s a perfect destination for a weekend getaway.
Where to Stay: Thompson Seattle.
Insider Tip: Explore the Ballard neighborhood for trendy shops, cafes, and breweries.
10. Portland, Oregon
Portland is known for its quirky culture, craft beer scene, and beautiful natural surroundings. You can spend your weekend exploring attractions like the Portland Art Museum, Powell’s City of Books, and the International Rose Test Garden. Don’t miss visiting the iconic Portlandia statue and taking a stroll along the Willamette River waterfront.
Portland’s neighborhoods each have their own unique character, from the hipster vibe of Alberta Arts District to the historic charm of Old Town Chinatown. And with its abundance of parks and green spaces, it’s a great destination for outdoor enthusiasts.
Where to Stay: The Nines, a Luxury Collection Hotel.
Insider Tip: Explore the food carts downtown for a taste of Portland’s diverse culinary scene.
11. Santa Fe, New Mexico
Santa Fe is a city steeped in history and culture, with its adobe architecture, vibrant arts scene, and rich Native American heritage. You can spend your weekend exploring attractions like the Georgia O’Keeffe Museum, the Palace of the Governors, and the Santa Fe Opera. Don’t miss taking a walk around the historic Plaza and visiting the nearby ancient ruins at Bandelier National Monument.
Santa Fe’s unique blend of Spanish, Native American, and Anglo influences gives it a distinctive character that you won’t find anywhere else. And with its beautiful desert landscape and clear blue skies, it’s a perfect destination for a weekend getaway.
Where to Stay: La Fonda on the Plaza.
Insider Tip: Take a day trip to Taos Pueblo to experience traditional Native American culture.
12. Aspen, Colorado
Aspen is a world-renowned destination for outdoor enthusiasts, with its world-class skiing, hiking, and mountain biking opportunities. You can spend your weekend exploring attractions like the Aspen Art Museum, the Maroon Bells, and the John Denver Sanctuary. Don’t miss taking a scenic drive along Independence Pass for breathtaking views of the Rocky Mountains.
Aspen’s charming downtown area offers plenty of shopping, dining, and nightlife options, making it a great destination for a weekend getaway year-round.
Where to Stay: The Little Nell.
Insider Tip: Visit the nearby town of Snowmass for even more outdoor adventures, including snowshoeing and cross-country skiing.
Midwest
13. Chicago, Illinois
Chicago is known for its stunning architecture, world-class museums, and vibrant cultural scene. You can spend your weekend exploring attractions like the Art Institute of Chicago, Millennium Park, and Navy Pier. Don’t miss taking an architecture boat tour along the Chicago River for a unique perspective on the city’s skyline.
Chicago’s diverse neighborhoods offer something for everyone, whether you’re interested in shopping on the Magnificent Mile, dining in Chinatown, or catching a show in the Theater District. And with its beautiful lakefront setting, it’s a perfect destination for a weekend getaway.
Where to Stay: The Langham, Chicago.
Insider Tip: Grab a slice of deep-dish pizza at Lou Malnati’s or Giordano’s for a true taste of Chicago.
14. Nashville, Tennessee
Nashville is known as the capital of country music, with its legendary honky-tonks, live music venues, and historic recording studios. You can spend your weekend exploring attractions like the Grand Ole Opry, the Country Music Hall of Fame, and the Ryman Auditorium. Don’t miss taking a stroll down Broadway to experience the city’s vibrant nightlife scene.
Nashville’s diverse neighborhoods offer something for everyone, whether you’re interested in history, culture, or cuisine. And with its friendly Southern hospitality, it’s a perfect destination for a weekend getaway.
Where to Stay: The Hermitage Hotel.
Insider Tip: Visit the nearby town of Franklin for charming boutiques, antique shops, and historic sites.
15. New Orleans, Louisiana
New Orleans is known for its vibrant music scene, rich culinary heritage, and colorful Mardi Gras celebrations. You can spend your weekend exploring attractions like the French Quarter, Jackson Square, and the Garden District. Don’t miss taking a steamboat cruise along the Mississippi River for panoramic views of the city skyline.
New Orleans’ diverse neighborhoods offer something for everyone, whether you’re interested in jazz clubs on Frenchmen Street, Creole cuisine in the Marigny, or historic architecture in the Bywater. And with its lively street performers, bustling markets, and festive atmosphere, it’s a perfect destination for a weekend getaway.
Where to Stay: The Roosevelt New Orleans.
Insider Tip: Take a cemetery tour to learn about the city’s unique above-ground burial practices.
16. Indianapolis, Indiana
Indianapolis is known for its world-class museums, thriving arts scene, and legendary sporting events. You can spend your weekend exploring attractions like the Indianapolis Museum of Art, the Indianapolis Motor Speedway, and the Canal Walk. Don’t miss taking a stroll through the historic neighborhoods of Lockerbie Square and Old Northside for a glimpse into the city’s past.
Indianapolis’ diverse cultural offerings make it a great destination for a weekend getaway, whether you’re interested in history, art, or sports. And with its vibrant downtown area, it’s easy to explore on foot or by bike.
Where to Stay: The Alexander.
Insider Tip: Visit the Indianapolis City Market for local produce, gourmet foods, and artisanal goods.
17. Milwaukee, Wisconsin
Milwaukee is known for its rich brewing heritage, vibrant arts scene, and beautiful lakefront setting. You can spend your weekend exploring attractions like the Harley-Davidson Museum, the Milwaukee Art Museum, and the Historic Third Ward. Don’t miss taking a brewery tour to sample some of the city’s best craft beers.
Milwaukee’s diverse neighborhoods offer something for everyone, whether you’re interested in history, culture, or outdoor activities. And with its scenic parks, bike trails, and beaches, it’s a perfect destination for a weekend getaway.
Where to Stay: The Pfister Hotel.
Insider Tip: Visit the Milwaukee Public Market for fresh seafood, artisanal cheeses, and locally made products.
18. Kansas City, Missouri
Kansas City is known for its barbecue, jazz music, and rich cultural heritage. You can spend your weekend exploring attractions like the Nelson-Atkins Museum of Art, the Negro Leagues Baseball Museum, and the American Jazz Museum. Don’t miss taking a stroll through the historic 18th and Vine District for a taste of the city’s vibrant jazz scene.
Kansas City’s diverse neighborhoods offer something for everyone, whether you’re interested in history, music, or food. And with its friendly Midwestern hospitality, it’s a perfect destination for a weekend getaway.
Where to Stay: The Fontaine.
Insider Tip: Visit the Crossroads Arts District for galleries, boutiques, and some of the city’s best restaurants.
19. Minneapolis, Minnesota
Minneapolis is known for its thriving arts scene, beautiful parks, and friendly Midwestern vibe. You can spend your weekend exploring attractions like the Minneapolis Institute of Art, the Walker Art Center, and the Chain of Lakes. Don’t miss taking a stroll across the Stone Arch Bridge for panoramic views of the city skyline.
Minneapolis’ diverse neighborhoods offer something for everyone, whether you’re interested in theater, music, or outdoor activities. And with its abundance of bike paths, hiking trails, and scenic overlooks, it’s a perfect destination for a weekend getaway.
Where to Stay: The Marquette Hotel.
Insider Tip: Visit the Midtown Global Market for international cuisine, artisanal products, and live entertainment.
20. St. Louis, Missouri
St. Louis is known for its iconic Gateway Arch, vibrant arts scene, and rich cultural heritage. You can spend your weekend exploring attractions like the City Museum, the Missouri Botanical Garden, and the St. Louis Zoo. Don’t miss taking a riverboat cruise along the Mississippi River for panoramic views of the city skyline.
St. Louis’ diverse neighborhoods offer something for everyone, whether you’re interested in history, culture, or outdoor activities. And with its friendly Midwestern hospitality, it’s a perfect destination for a weekend getaway.
Where to Stay: The Ritz-Carlton, St. Louis.
Insider Tip: Visit the Soulard neighborhood for historic architecture, live music, and some of the city’s best barbecue.
21. Cincinnati, Ohio
Cincinnati is known for its rich history, vibrant arts scene, and stunning riverfront setting. You can spend your weekend exploring attractions like the Cincinnati Art Museum, the Cincinnati Zoo & Botanical Garden, and the National Underground Railroad Freedom Center. Don’t miss taking a stroll through the historic Over-the-Rhine neighborhood for charming boutiques, cafes, and breweries.
Cincinnati’s diverse cultural offerings make it a great destination for a weekend getaway, whether you’re interested in history, art, or food. And with its beautiful parks, scenic overlooks, and riverfront trails, it’s easy to explore the city on foot or by bike.
Where to Stay: The Westin Cincinnati.
Insider Tip: Visit Findlay Market for local produce, gourmet foods, and artisanal goods.
These destinations offer a diverse range of experiences, from vibrant city life to serene natural beauty, making them perfect for a weekend getaway. Whether you’re interested in history, culture, or outdoor adventures, you’ll find something to explore in these cities across the United States.
Northeast
22. Boston, Massachusetts
Boston is steeped in history, with its cobblestone streets, revolutionary landmarks, and world-class museums. You can spend your weekend exploring attractions like the Freedom Trail, Fenway Park, and the Museum of Fine Arts. Don’t miss taking a stroll through Boston Common and the Public Garden for a taste of the city’s natural beauty.
Boston’s diverse neighborhoods offer something for everyone, whether you’re interested in history, culture, or cuisine. And with its charming waterfront setting, it’s a perfect destination for a weekend getaway.
Where to Stay: The Liberty, a Luxury Collection Hotel.
Insider Tip: Visit the North End neighborhood for authentic Italian cuisine and historic sites like the Paul Revere House.
23. Philadelphia, Pennsylvania
Philadelphia is known for its rich history, vibrant arts scene, and diverse culinary offerings. You can spend your weekend exploring attractions like Independence Hall, the Liberty Bell, and the Philadelphia Museum of Art. Don’t miss taking a stroll through Reading Terminal Market for a taste of the city’s food scene.
Philadelphia’s diverse neighborhoods offer something for everyone, whether you’re interested in history, culture, or outdoor activities. And with its convenient location between New York City and Washington, D.C., it’s a perfect destination for a weekend getaway.
Where to Stay: The Ritz-Carlton, Philadelphia.
Insider Tip: Visit the Philadelphia Magic Gardens for a unique outdoor art installation made of recycled materials.
24. Burlington, Vermont
Burlington is known for its stunning natural beauty, vibrant arts scene, and progressive culture. You can spend your weekend exploring attractions like the Church Street Marketplace, the ECHO Leahy Center for Lake Champlain, and the Shelburne Museum. Don’t miss taking a stroll along the Burlington Bike Path for panoramic views of Lake Champlain and the Adirondack Mountains.
Burlington’s diverse neighborhoods offer something for everyone, whether you’re interested in outdoor activities, cultural events, or farm-to-table dining. And with its friendly vibe and laid-back atmosphere, it’s a perfect destination for a weekend getaway.
Where to Stay: Hotel Vermont.
Insider Tip: Visit the nearby town of Stowe for world-class skiing, hiking, and outdoor adventures.
25. Providence, Rhode Island
Providence is known for its historic architecture, vibrant arts scene, and eclectic culinary offerings. You can spend your weekend exploring attractions like WaterFire, the Rhode Island School of Design Museum, and the Roger Williams Park Zoo. Don’t miss taking a stroll through the historic Federal Hill neighborhood for authentic Italian cuisine and charming boutiques.
Providence’s diverse neighborhoods offer something for everyone, whether you’re interested in history, culture, or outdoor activities. And with its picturesque waterfront setting, it’s a perfect destination for a weekend getaway.
Where to Stay: The Dean Hotel.
Insider Tip: Visit the Providence Athenaeum for a glimpse into the city’s literary history and a cozy reading nook.
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